physical IRIfile:/home/genordo/Work/ORDO/ORDO_en_2.7.owl
loaded ontology 1 in loader 
loading ontology 1 complete
physical IRIfile:/home/genordo/Work/ORDO/ORDO_en_2.8.owl
loaded ontology 1 in loader 
loading ontology 2 complete

@Ontology Change Summary
@First ontology IRI: Optional.of(http://www.orpha.net/ontology/ORDO_en_2.7.owl)
@Second ontology IRI: Optional.of(http://www.orpha.net/ontology/ORDO_en_2.8.owl)
@Number of classes changed: 589
@Number of classes added: 211
@Number of classes deleted: 14

@Classes modified from previous

---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_86885
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_86885> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_86885> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2229
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2229> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_86867
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_86867> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_86867> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_86867> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2201
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2201> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2201> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "25.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_199299
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_199299> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_397755
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_397755> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98740>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_397755> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_352298>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_397755> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_370980
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370980> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370980> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_370968
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370968> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370968> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_370959
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370959> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370959> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_774
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_774> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_774> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "16.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_774> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "20.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_774> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_443167
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_443167> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_443167> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_443167> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_443167> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_757
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_757> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "180.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_757> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "80.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_740
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_740> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300766>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_731
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_731> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_731> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156604>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_731> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_731> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410073>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "5.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_731> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_101939>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_731> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_731> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "1.17"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_370348
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370348> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370348> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370348> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_723
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_723> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_88619
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_88619> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_88619> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "14.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_88619> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_88619> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_88619> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "11.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_88619> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_717
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_717> <http://www.orpha.net/ORDO/Orphanet_156629>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_714
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_714> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_701
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_701> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_314662
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_314662> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_530313>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_314662> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93460>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2189
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2189> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_97355
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97355> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97355> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_120730
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120730> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_287>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120730> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_90318>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120730> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_90309>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_97336
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97336> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_120728
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120728> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_287>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120728> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_90309>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120728> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_90318>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_464366
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_464366> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_120707
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120707> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_1899>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120707> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_99876>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_120704
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120704> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_287>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120704> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_1899>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120704> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_90318>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120704> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_230845>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120704> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_99875>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120704> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_90309>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_168796
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_168796> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_217656
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_217656> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_221091
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_221091> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_221091> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_221091> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1877
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1877> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_1877> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1877> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_206634>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_157832
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_157832> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "4.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_157832> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_157832> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "6.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_397615
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_397615> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_397615> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_443084
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_443084> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_443084> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_685
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_685> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "4.2"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_685> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "5.2"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_684
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_684> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98738>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_684> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_352298>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_684> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_363976
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363976> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_682
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_682> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98738>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_682> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_352298>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_682> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_681
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_681> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98741>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_681> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98740>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_681> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_681> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98738>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_681> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_352298>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_681> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_672
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_672> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_158061
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_158061> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_158061> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_158061> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_158061> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_661
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_661> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156610>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_661> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_101944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_279919
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_279919> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_158057
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_158057> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_158057> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_636
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_636> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410065>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "24.46"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_636> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_536391>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_636> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410065>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "23.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3032
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3032> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156180>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_614
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_614> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98739>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_614> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_352298>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_614> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_612
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_612> <http://www.orpha.net/ORDO/Orphanet_98738>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_612> <http://www.orpha.net/ORDO/Orphanet_71864>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_612> <http://www.orpha.net/ORDO/Orphanet_352298>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98520
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98520> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98520> <http://www.orpha.net/ORDO/Orphanet_377794>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98520> <http://www.orpha.net/ORDO/Orphanet_269194>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98520> <http://www.orpha.net/ORDO/Orphanet_98519>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_97287
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97287> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97287> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97287> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97287> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_269762
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_269762> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_85172>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2081
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2081> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409939>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_97252
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97252> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98519>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97252> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98520>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_413011
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_413011> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_2593>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_413011> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_327767> <http://www.orpha.net/ORDO/Orphanet_2593>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_93552
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93552> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93552> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93552> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93552> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_93552> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410006>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.32"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_70470
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_70470> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_181425>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_70470> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70470> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409931>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70470> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_31709
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_31709> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_457378
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_457378> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_300179
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_300179> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300179> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_536545>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300179> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_300179> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_307
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_307> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98749>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_363618
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363618> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300766>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_209004
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_209004> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_209004> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_404514
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_404514> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_404514> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_439897
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_439897> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_439881
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_439881> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_439881> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_597
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_597> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98742>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3342
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3342> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "102.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3342> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "80.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_569
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_569> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_569> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98745>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_295239
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_295239> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_530313>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_564
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_564> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_564> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_485426
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_485426> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289390
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410207>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "37.15"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "6.92"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410076>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "5.3"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410023>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409980>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "165.98"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410100>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "30.91"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410207>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "9.5"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410217>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409980>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "207.83"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410193>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "3.9"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410225>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "3.95"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410225>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "3.9"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_356996
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_356996> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "5.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_356996> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "3.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_321364
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_321364> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_2752>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_536
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410150>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "14.7"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410225>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "53.6"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410207>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "37.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410130>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409978>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "64.2"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410065>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "28.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410066>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "47.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410109>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "20.6"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_534
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_534> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_514016
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_514016> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "11q25"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1354
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1354> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_404574>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1354> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_294955>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1354> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156532>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_280926
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280926> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280926> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280926> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280926> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_280921
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280921> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280921> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280921> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280921> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_399329
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_399329> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_399329> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_399329> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_280914
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280914> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280914> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280914> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280914> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_71279
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_71279> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_71279> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "100.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71279> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_71279> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_490415
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_490415> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_261323>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_490415> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_3323>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_330050
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_330050> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_330050> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_330050> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "11.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_330050> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_269200
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_269200> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Morphological anomaly"@en) <http://www.orpha.net/ORDO/Orphanet_269200> <http://www.orpha.net/ORDO/Orphanet_377791>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_269200> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_269200> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98520>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_171719
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_171719> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_284993>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_228318
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_228318> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_228318> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_33208>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_228318> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_228318> <http://www.orpha.net/ORDO/Orphanet_377796>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_228318> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_228318> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409976>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_228315
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_228315> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_228315> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_228315> <http://www.orpha.net/ORDO/Orphanet_377796>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_228315> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_33208>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_228315> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_331972
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_331972> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_327767> <http://www.orpha.net/ORDO/Orphanet_528091>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_122376
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_122376> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_178330>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_157973
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_157973> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_33475
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_33475> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_453510
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_453510> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_157965
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_157965> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_157965> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_536471>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_157965> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_157965> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_453504
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_453504> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "10.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_453504> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "2.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_118532
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_118532> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410296> <http://www.orpha.net/ORDO/Orphanet_526>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_474
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_474> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_474> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_118561
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_118561> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_327767> <http://www.orpha.net/ORDO/Orphanet_100093>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_118561> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_100093>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_291802
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_291802> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_1401>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_84081
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_84081> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250811>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_238998
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238998> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q25.3"^^xsd:string))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238998> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q21.1"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_442
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_442> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410097>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "45.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_423
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_423> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98742>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_423> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_352298>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_423> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_314394
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_314394> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_60033
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_60033> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1956
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1956> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1956> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_140474>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_1956> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410204>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.36"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1956> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79385>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1956> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_1956> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_1956> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1956> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_1956> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410225>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "1.3"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_1956> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410157>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "1.5"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1956> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409941>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_1956> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410157>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.29"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_1956> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410150>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "15.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1949
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1949> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1945
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1945> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98749>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1943
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1943> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "3.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1943> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "29.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1934
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1934> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1934> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_101063
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_101063> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_108971>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1906
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1906> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410073>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "1.2"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1906> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "1.02"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1906> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410172>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "11.7"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1906> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410205>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "1.3"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1906> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410097>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "1.3"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1906> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410014>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409976>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "0.5"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1906> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410147>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "1.7"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1900
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_1900> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1900> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_536545>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1900> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_1900> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2044
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2044> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2044> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2044> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "87.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2044> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_93323
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93323> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93323> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_453499
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_453499> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "12.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_453499> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156532>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_453499> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "15.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98977
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98977> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98977> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98977> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_75858
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75858> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98922
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98922> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98519>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98922> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98520>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98913
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98913> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98738>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98905
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98905> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98742>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_506307
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_506307> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_506307> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_506307> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3451
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3451> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_338
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_338> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "7.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_338> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_338> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_338> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79386>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_338> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_338> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183487>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_399180
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_399180> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_399180> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1872
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1872> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156171>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1872> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156174>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1871
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1871> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1871> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156171>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79156
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79156> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_68385>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79156> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79156> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_64
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_300
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_93292
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93292> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93292> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_261323
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_261323> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_477794>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_261323> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_261323> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102283>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_261323> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_261323> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_138047>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_261323> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "14.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_261323> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_261323> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_261323> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "12.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_293199
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293199> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293199> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293199> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293199> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293199> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_487075
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_487075> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19q13.32"^^xsd:string))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_487075> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19q13"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_124012
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_124012> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_327767> <http://www.orpha.net/ORDO/Orphanet_90001>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_120326
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_120326> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317345> <http://www.orpha.net/ORDO/Orphanet_334>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_124007
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_124007> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_327767> <http://www.orpha.net/ORDO/Orphanet_90001>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_363540
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363540> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_538238>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_35107
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_35107> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "10.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_35107> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "9.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2168
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2168> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2168> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2168> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "4.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2168> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_2168> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2168> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2168> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79187>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2168> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_209484
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_209484> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q11.2"^^xsd:string))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_209484> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q11.1"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98892
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98892> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2185
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2185> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79486
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79486> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79486> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_79486> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79486> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409941>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79486> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79486> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_458833>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_525677
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_525677> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79474
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79474> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300766>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_240085
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_240085> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_306666>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98853
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98853> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_157798
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_157798> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_157798> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98837
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98837> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_98837> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98837> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_86851>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98836
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98836> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98836> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_86851>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_98836> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98827
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98827> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_251633
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251633> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251633> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_301>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_251633> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_251636
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251636> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251636> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_251633>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_251636> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_251636> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.16"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_251636> <http://www.orpha.net/ORDO/Orphanet_377797>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251636> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409941>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_157769
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_157769> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_108971>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_91385
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91385> <http://www.orpha.net/ORDO/Orphanet_658>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_91385> <http://www.orpha.net/ORDO/Orphanet_377794>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_91385> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91385> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_658>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98809
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98809> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_296
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_296> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_296> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_91349
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91349> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91349> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91349> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_213807
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_213807> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213807> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213807> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_180229
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180229> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180229> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_213802
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213802> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213802> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213802> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_272
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_272> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_264
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_264> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_309015
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_309015> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_309015> <http://www.orpha.net/ORDO/Orphanet_377796>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_309108
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_309108> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_280675
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_280675> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_521305>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_217
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_217> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98519>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_217> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98520>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_391677
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_391677> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "39.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_391677> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "34.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1460
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1460> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1460> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1460> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_201295
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_201295> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410296> <http://www.orpha.net/ORDO/Orphanet_2593>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_201295> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410296> <http://www.orpha.net/ORDO/Orphanet_2593>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_168782
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_168782> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_103908
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_103908> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_103908> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98768
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98768> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98758
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98758> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98745>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98686
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98686> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_213787
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_213787> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213787> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213787> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_370396
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370396> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370396> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370396> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370396> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_213777
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213777> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213777> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79344
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79344> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79344> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_79344> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79344> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_176>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79344> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79344> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_36913
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_36913> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_36913> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_36913> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_370334
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370334> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370334> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370334> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_363478
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363478> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_182
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_182> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_182> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_264978
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_264978> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_264978> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_363454
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_363454> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363454> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_363454> <http://www.orpha.net/ORDO/Orphanet_377796>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_363447
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363447> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_363447> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "97.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363447> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_363447> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363447> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_363447> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_458803
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_458803> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98745>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_181425
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_181425> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_181425> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_181425> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_181425> <http://www.orpha.net/ORDO/Orphanet_377794>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_181425> <http://www.orpha.net/ORDO/Orphanet_181422>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_110
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_110> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156180>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_110> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_110> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156183>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1662
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1662> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300766>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_444490
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_444490> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_181422>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_444490> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_181425>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_120184
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_120184> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19q13.42"^^xsd:string))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_120184> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19q13.4"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_54370
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_54370> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_418959
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_418959> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_418959> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_54368
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_54368> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_54368> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_159456
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_159456> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_88616>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289877
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_289877> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289877> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_123982
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_123982> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_83648>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3323
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3323> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3323> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3323> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3323> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_3323> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3323> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_139039>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3323> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "2.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98733
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98733> <http://www.orpha.net/ORDO/Orphanet_536391>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_36899
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_36899> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98741>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98772
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98772> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98784
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98784> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98784> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98748>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_502363
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_502363> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_502363> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_502363> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_502363> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_159172
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_159172> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_2907>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_33069
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_33069> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_33069> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98749>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79211
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79211> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79211> <http://www.orpha.net/ORDO/Orphanet_181422>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_79211> <http://www.orpha.net/ORDO/Orphanet_377794>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3405
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3405> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "66.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3405> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3405> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3405> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3405> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "55.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3402
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3402> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_75501
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_75501> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_275736>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_75501> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_75501> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_398980
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_398980> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_398980> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_398980> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410225>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.678"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_363494
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363494> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_123878
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_123878> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_93591>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_435628
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_435628> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_317726
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_317726> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_103908>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_500478
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_500478> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_500478> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_500478> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_500464
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_500464> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_500464> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_54260
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_54260> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1530
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1530> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1530> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98641>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1530> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_139393>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1530> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_1530> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1530> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_522548>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1515
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1515> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_120047
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_120047> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19q13.2"^^xsd:string))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_120047> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19q13.1"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_230845
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_230845> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "3.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_233655>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_230845> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_230845> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_521438
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_521438> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_220497
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_220497> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156180>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_220493
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_220493> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_168099
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_168099> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_521438>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_521450
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_521450> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98856
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98856> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300758>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_36387
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_36387> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98749>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_36387> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_75496
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75496> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_536471>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75496> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75496> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_75496> <http://www.orpha.net/ORDO/Orphanet_377796>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75496> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75496> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93446>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75496> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_371200>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_75496> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75496> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_371195>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_442835
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_442835> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98749>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_442835> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_442835> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98745>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_442835> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98871
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98871> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98871> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79154
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79154> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79154> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289385
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289385> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_289385> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79137
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79137> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_90120
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90120> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90120> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91024>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_324581
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_324581> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98742>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_329217
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_329217> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_329217> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.35"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_370114
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370114> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_370114> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_391711>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_370114> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_88673
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_88673> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_88673> <http://www.orpha.net/ORDO/Orphanet_424936>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_88673> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_424936>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_88673> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_439218
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_439218> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_84142
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_84142> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98750>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_84142> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1488
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1488> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102283>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1488> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_330206>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1488> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102285>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_280365
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280365> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300763>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_352665
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_352665> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "2.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_352665> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "13.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_470544
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470544> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_88616>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_138366
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_138366> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317344> <http://www.orpha.net/ORDO/Orphanet_530995>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_138366> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317344> <http://www.orpha.net/ORDO/Orphanet_98837>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_77243
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_77243> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_77243> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1435
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1435> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1435> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "13.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1435> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "4.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1434
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1434> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_1434> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1434> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_519321>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_166108
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_166108> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289661
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289661> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1401
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1401> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156237>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1401> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79373>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1401> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_1401> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1401> <http://www.orpha.net/ORDO/ObsoleteClass>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_499182
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_499182> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_499182> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_499182> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319487
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319487> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_100989
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100989> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_66629
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_66629> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "24.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_66629> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "8.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_66628
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_66628> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_66628> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_66627
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_66627> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_66627> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_66627> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3287
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3287> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410168>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.092"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3287> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410168>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409976>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "0.46"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_121853
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_121853> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_82004>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_508501
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_508501> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_93314
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93314> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_124094
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_124094> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_327767> <http://www.orpha.net/ORDO/Orphanet_35737>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_124094> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_35737>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_206599
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_206599> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_206599> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_439196
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_439196> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_439196> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3207
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3207> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102283>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_141127
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_141127> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_141127> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_454887
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_454887> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_306666>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2580
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2580> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2580> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2580> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_2580> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2580> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_180226
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180226> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180226> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_435438
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_435438> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1396
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1396> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1396> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98683>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1396> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93547>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_1396> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1396> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1396> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1396> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_522520>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1396> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93587>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_180242
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180242> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180242> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_180247
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180247> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180247> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1377
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1377> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1377> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1361
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1361> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_447874>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Biological anomaly"@en) <http://www.orpha.net/ORDO/Orphanet_1361> <http://www.orpha.net/ORDO/Orphanet_377790>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_1361> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289586
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289586> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250811>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_210159
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_210159> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_210159> <http://www.orpha.net/ORDO/Orphanet_377796>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_64720
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64720> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64720> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64720> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64720> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_485350
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_485350> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_538238>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289535
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_289535> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_289527>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289527
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289527> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289527> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289527> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289527> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_217587>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_289527> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_289527> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289527> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_309136>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_289527> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2665
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2665> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2665> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3197
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3197> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98747>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3191
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3191> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102285>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3191> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_330206>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3191> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183570>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3191> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_139021>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3191> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156532>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3191> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98628>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_238624
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238624> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238624> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319322
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319322> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319322> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319322> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319314
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319314> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319314> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_217071>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_319314> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_69083
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_69083> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_69083> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_69083> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_69083> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_137935
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_137935> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_118546
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_118546> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_521411>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_255229
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_255229> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_64694
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64694> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_118525
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_118525> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410296> <http://www.orpha.net/ORDO/Orphanet_1956>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3102
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3102> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_364574>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_521414
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_521414> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_71529
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71529> <http://www.orpha.net/ORDO/Orphanet_179490>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_71529> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_71529> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71529> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_179490>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_71528
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71528> <http://www.orpha.net/ORDO/Orphanet_179490>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_71528> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_71528> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71528> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_179490>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_206470
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_206470> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_521406
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_521406> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_331206
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_331206> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_447881
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_447881> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_447881> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_352487
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352487> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352487> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352487> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_352487> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "8.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_352487> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_352487> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352487> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409932>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352487> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98464>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352487> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_294959>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_352479
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352479> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352479> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_494550
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_494550> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_494550> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_494550> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_494550> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_494451
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_494451> <http://www.orpha.net/ORDO/Orphanet_377797>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_494451> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_444069
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_444069> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_95719
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_95719> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_289478
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289478> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_289478> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "36.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_289478> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319298
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319298> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319298> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_93932
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93932> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319276
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319276> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319276> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319266
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319266> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_209335
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_209335> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319244
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319244> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319239
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319239> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_521390
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_521390> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319229
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319229> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98267
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98267> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_77828>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_98267> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98267> <http://www.orpha.net/ORDO/Orphanet_377794>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98267> <http://www.orpha.net/ORDO/Orphanet_77828>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319223
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319223> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_79084
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_79084> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300763>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_331176
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_331176> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_331176> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_252164
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_252164> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_252164> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_82004
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_82004> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82004> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_285014>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82004> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82004> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_82004> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82004> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409934>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_100056
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100056> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_528663>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100056> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91385>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_160320
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_160320> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "12p12.3"^^xsd:string))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_160320> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "12p13"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_280200
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_280200> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_391723
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_391723> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_391723> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_294415
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_294415> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156180>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_294415> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_122
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_122> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_213574
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213574> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213574> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_178396
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_178396> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250808>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_244305
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_244305> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "12.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_244305> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "6.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1143
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1143> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_95427
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_95427> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_306731
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_306731> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306731> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306731> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306731> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_178330
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_178330> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_178330> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_178330> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_178330> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "10.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_178330> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_178330> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_182043>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_178307
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_178307> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_440233
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_440233> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_227535
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_227535> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_227535> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_309020
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_309020> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_309020> <http://www.orpha.net/ORDO/Orphanet_377796>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_440221
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_440221> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_140969
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140969> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_140966
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140966> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250811>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_140944
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140944> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_530313>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_791
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_791> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156168>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_791> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156171>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_97335
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_97335> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97335> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97335> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_97337
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97337> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97337> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_97338
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97338> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2907
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_2907> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2907> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2907> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_222628>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2907> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "41.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2907> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2907> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_306539>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_2907> <http://www.orpha.net/ORDO/Orphanet_377796>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_140976
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140976> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_238569
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238569> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_529974>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238569> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_271870>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238569> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_104012>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238569> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_165655>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_238569> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_169361>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_244
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_244> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156171>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1078
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1078> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "7.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1078> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1078> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102283>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1078> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1078> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "6.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_165805
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_165805> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_279925
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_279925> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_95707
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_95707> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_95707> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_269953
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_269953> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_535453>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_269953> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_444490>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1035
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1035> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409951>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_139507
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_139507> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_139507> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_512465
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_512465> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19p13.3"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_158048
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_158048> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_158048> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_313892
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_313892> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_313892> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "14.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_313892> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "12.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_313892> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2967
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2967> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2967> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_121474
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_121474> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_370114>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_163921
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_163921> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_163921> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_209989
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_209989> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_209989> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_468831
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_468831> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_528084>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_468831> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_777>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_137667
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_137667> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_536391>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2908
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2908> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183490>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2908> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79390>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_2908> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_2908> <http://www.orpha.net/ORDO/Orphanet_377796>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2908> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_306539>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2903
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2903> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2903> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_36235
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_36235> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_71272
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71272> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71272> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_137605
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_137605> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_536391>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_358431
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_358431> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317344> <http://www.orpha.net/ORDO/Orphanet_268973>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_306
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_97
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_97> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98745>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_213792
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213792> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213792> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213792> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_213792> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_420789
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_420789> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98033>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_86
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_86> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_86> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_82
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250811>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_494418
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_494418> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_180312>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_494418> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_494418> <http://www.orpha.net/ORDO/Orphanet_180312>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_494418> <http://www.orpha.net/ORDO/Orphanet_377794>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_74
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_74> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_74> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_65
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_65> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156174>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_60
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_60> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250808>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_180234
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180234> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180234> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_180234> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_494454
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_494454> <http://www.orpha.net/ORDO/Orphanet_377797>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_494454> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_306539
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306539> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_306539> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_306539> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306539> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306539> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306539> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306539> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79390>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306539> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_306539> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183490>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_123271
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_123271> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317348> <http://www.orpha.net/ORDO/Orphanet_530995>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_123271> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317348> <http://www.orpha.net/ORDO/Orphanet_98837>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_123271> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317348> <http://www.orpha.net/ORDO/Orphanet_98836>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_93951
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93951> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_93951> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93951> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_2076>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93951> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409934>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2875
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2875> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_424107
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_424107> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98742>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_31205
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_31205> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2850
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2850> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2850> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "15.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2850> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_121382
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_121382> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_530849>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_121382> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_70470>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2848
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2848> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2848> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2848> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_137599
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_137599> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_137583
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_137583> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_137583> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_352298
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352298> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_352298> <http://www.orpha.net/ORDO/Orphanet_377794>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_352298> <http://www.orpha.net/ORDO/Orphanet_183497>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2809
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2809> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2809> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2809> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_330909
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_330909> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "14q32.13"^^xsd:string))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_330909> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "14q32.1"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_201300
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_201300> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410296> <http://www.orpha.net/ORDO/Orphanet_2593>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_201300> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410296> <http://www.orpha.net/ORDO/Orphanet_2593>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_199343
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_199343> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_70474
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70474> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70474> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_64280
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64280> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98749>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64280> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98745>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_93315
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93315> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93315> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_93315> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99889
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99889> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99889> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_213812
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213812> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_213812> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99876
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99876> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_1899>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99876> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_99876> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99876> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99876> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99875
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99875> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_1899>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99875> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99875> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99875> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_99875> <http://www.orpha.net/ORDO/Orphanet_377795>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99871
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99871> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99871> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99861
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99861> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99861> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99860
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99860> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_64692
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_64692> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_412
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_412> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_181422>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_412> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79211>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_53689
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_53689> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_53689> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_458785
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_458785> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_420402
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_420402> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_420402> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_71526
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71526> <http://www.orpha.net/ORDO/Orphanet_179490>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_71526> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_71526> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_71526> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_179490>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99803
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99803> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156610>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99803> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_101944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99802
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99802> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_530313>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_465
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_465> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250808>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_100055
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100055> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_528663>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100055> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91385>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_100054
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100054> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_528647>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100054> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91378>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_46488
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_46488> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_100050
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100050> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_528623>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100050> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91378>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_276621
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_276621> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_276621> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_276621> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_201108
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_201108> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_535458>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_201108> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_444490>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_123112
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_123112> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317345> <http://www.orpha.net/ORDO/Orphanet_70470>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_521445
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_521445> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_494547
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_494547> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_494547> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_178145
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_178145> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98742>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319234
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319234> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2798
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2798> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_163209>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2795
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2795> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2795> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2795> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2795> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409951>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_85445
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_85445> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_85445> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_85445> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3085
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3085> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_69126
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_69126> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "53.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_69126> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "34.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3096
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3096> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3096> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3096> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3096> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319254
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319254> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_85408
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_85408> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_179490
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_179490> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98267>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_179490> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_179490> <http://www.orpha.net/ORDO/Orphanet_377794>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_179490> <http://www.orpha.net/ORDO/Orphanet_98267>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_90153
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90153> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300763>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2736
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2736> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2736> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "5.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2736> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "3.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2736> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_121250
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_121250> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_352487>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_459353
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_459353> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250811>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_500135
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_500135> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_251643
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_251633>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409941>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_251643> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_251643> <http://www.orpha.net/ORDO/Orphanet_377797>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_251643> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_199247
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_199247> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250811>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_251639
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_251639> <http://www.orpha.net/ORDO/Orphanet_377797>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251639> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251639> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_251633>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_251639> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_225372
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_225372> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_166272>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_294026
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_294026> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_294026> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99741
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99741> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98742>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_395954
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_395954> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317348> <http://www.orpha.net/ORDO/Orphanet_530792>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_395954> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317348> <http://www.orpha.net/ORDO/Orphanet_251636>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_101685
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_101685> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_101685> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_420561
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_420561> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "8.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_420561> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "7.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3132
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3132> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "4.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3132> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "2.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319303
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319303> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319303> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319308
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319308> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319308> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319308> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319308> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319308> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_208981
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_208981> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_208981> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3156
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3156> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3156> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156180>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319319
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319319> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319325
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319325> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319325> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2688
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2688> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_163934
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_163934> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_401973
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_401973> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_401973> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "24.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_401973> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "19.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_404454
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_404454> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_404454> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183484>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_404454> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98604>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_404454> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_281244>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_404454> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79382>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2679
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2679> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2679> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98497>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_2679> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_94093
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_94093> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409939>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_94093> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_33402
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_33402> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_33402> <http://www.orpha.net/ORDO/Orphanet_377796>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_43393
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_43393> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98750>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_46627
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_46627> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "109.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_46627> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "10.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_163988
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_163988> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_163988> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409932>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_163988> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_163988> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98464>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_163988> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_163988> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_90642>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_163988> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_163988> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_57196
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_57196> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_57196> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "58.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_57196> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_57196> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_57196> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_251529
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251529> <http://www.orpha.net/ORDO/Orphanet_108999>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251529> <http://www.orpha.net/ORDO/Orphanet_521132>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_51608
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_51608> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_51608> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "300.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_51608> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_51608> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_300751
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300751> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300751> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_169186
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_169186> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98742>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_117952
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_117952> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_1435>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_117952> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_163988>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_90309
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90309> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_287>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90309> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90309> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_90309> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "5.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_90309> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90309> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1397
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1397> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "2.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1397> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_1397> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_169160
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_169160> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_169154
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_169154> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_70590
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70590> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70590> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_35062
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_35062> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_35062> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_293181
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293181> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_85110
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_85110> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_85110> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_85110> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250808>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_655
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_655> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_655> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156180>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3208
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3208> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3208> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_91378
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91378> <http://www.orpha.net/ORDO/Orphanet_98053>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91378> <http://www.orpha.net/ORDO/Orphanet_658>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_91378> <http://www.orpha.net/ORDO/Orphanet_377794>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_91378> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91378> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_658>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_91378> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98053>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_85295
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_85295> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_521411
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_521411> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_83467
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_83467> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98750>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_83467> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2596
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2596> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2596> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2596> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2596> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2596> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2593
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2593> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2593> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2593> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3299
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3299> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2578
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2578> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2576
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2576> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "150.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2576> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410065>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "2.7"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2576> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2576> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "140.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_90318
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90318> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_90318> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90318> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_287>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90318> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90318> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_293987
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293987> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156610>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293987> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_293987> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "158.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293987> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409939>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293987> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_101944>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_293987> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "48.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_293987> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409931>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2536
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "5.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2536> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "4.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2535
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2535> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2535> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_522568>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_2535> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2535> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2535> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_519286>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2535> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "3.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_140927
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140927> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140927> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_285106
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_285106> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_3455>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_213751
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213751> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_213751> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_90280
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90280> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_90280> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_90280> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "70.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90280> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90280> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90280> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90280> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_94058
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_94058> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_94058> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2505
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2505> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2505> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_502623
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_502623> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_486>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1454
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1454> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1454> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156165>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1482
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1482> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_839
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_839> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410065>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "12.2"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_839> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_839> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410065>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409975>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "12.2"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_839> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_450322
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_450322> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_450322> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_329249
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_329249> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_329249> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_436871
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_436871> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_55654>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_228426
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_228426> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363300>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3390
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "2.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3390> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_3390> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_369891
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_369891> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "26.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_369891> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "4.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2473
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2473> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2473> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156183>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_369873
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_369873> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_369873> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2442
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2442> <http://www.orpha.net/ORDO/Orphanet_238510>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_2442> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2442> <http://www.orpha.net/ORDO/Orphanet_158038>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2442> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_238510>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2442> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_158038>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_2442> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_90186
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90186> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90186> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_251332
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251332> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_415286
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_415286> <http://www.orpha.net/ORDO/Orphanet_309816>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_415286> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_415286> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_415286> <http://www.orpha.net/ORDO/Orphanet_68385>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_415286> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_309816>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_415286> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_68385>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_415286> <http://www.orpha.net/ORDO/Orphanet_377792>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3105
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3105> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3105> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3105> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3105> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3105> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_3105> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "2.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3105> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102284>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_3105> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3105> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_330197>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_122887
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_122887> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_530838>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_380
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_380> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_251523
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_251523> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "18.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_251523> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "5.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_397946
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_397946> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_300525
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300525> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_319213
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_319213> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_276280
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_276280> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_530313>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_276280> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93460>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_37612
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_37612> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98746>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_95715
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_95715> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_65759
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_65759> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_363250>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_900
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_900> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_900> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_900> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_900> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410224>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "1.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_900> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410198>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.49"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_900> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410065>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.93"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_900> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_900> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410157>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "1.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_900> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410157>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "1.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_900> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_900> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410198>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.49"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_900> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410224>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "1.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_900> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410065>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.93"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_3466
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_3466> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93459>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_100051
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100051> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_528623>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100051> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91378>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2387
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2387> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2382
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2382> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98744>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2382> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98749>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_295243
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_295243> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_530313>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2377
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2377> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156183>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_99873
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99873> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_99873> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99873> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99873> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99873> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2364
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2364> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_140286
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140286> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_100093
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_100093> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_502366
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_502366> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_502366> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_35737
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_35737> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2348
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2348> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300763>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2342
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2342> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2342> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2337
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2337> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2337> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_353524
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_353524> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_791>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_35708
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_35708> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "140.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_35708> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "100.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2318
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2318> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156162>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2302
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2302> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_522043
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_522043> <http://www.orpha.net/ORDO/Orphanet_363300>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_523000
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_523000> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_523000> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_523000> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_523000> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_527276
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527276> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527276> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_527276> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "15.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_527276> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527276> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_209341
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_209341> <http://www.orpha.net/ORDO/Orphanet_377795>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_209341> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_209341> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "37.0"^^xsd:float)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_209341> <http://www.orpha.net/ORDO/Orphanet_377796>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_209341> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_309031
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_309031> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_168940
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_168940> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_168940> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_168940> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_90026
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_90026> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409977>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410225>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "1.1"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_90026> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90026> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_90026> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90026> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_90026> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "30.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_86909
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_86909> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_210584
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_210584> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_210584> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_210584> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_210584> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_1692
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1692> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1692> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_1692> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "18.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_317857
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_317857> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_70470>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_317857> <http://www.orpha.net/ORDO/Orphanet_410298>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_317857> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19p13.3"^^xsd:string))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_37553
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_37553> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98741>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_37553> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_352298>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_37553> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_71864>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_279922
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_279922> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_60040
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_60040> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_530313>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_60040> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93460>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_313822
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_313822> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_93591>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_886
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_886> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_156177>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_876
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_876> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_876> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_98855
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98855> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_300755>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_972
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_972> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98741>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_831
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_831> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_831> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_443227
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_443227> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_456318
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_456318> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_68354>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_395960
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_395960> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317348> <http://www.orpha.net/ORDO/Orphanet_530792>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_395960> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317348> <http://www.orpha.net/ORDO/Orphanet_251636>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_494448
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_494448> <http://www.orpha.net/ORDO/Orphanet_377797>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_494448> <http://www.orpha.net/ORDO/Orphanet_377788>)
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_313884
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_313884> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_313884> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "11.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_313884> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_313884> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_313884> <http://www.orpha.net/ORDO/Orphanet_377789>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_313884> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "6.0"^^xsd:float)))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_2286
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2286> <http://www.orpha.net/ORDO/ObsoleteClass>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_2286> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_2286> <http://www.orpha.net/ORDO/Orphanet_377796>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2286> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183580>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2286> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_280200>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2286> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409931>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2286> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2286> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_139042>))
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2286> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410006>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "2.0"^^xsd:float)))
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2286> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
---
Class changed: IRI http://www.orpha.net/ORDO/Orphanet_179494
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_179494> <http://www.orpha.net/ORDO/Orphanet_179490>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_179494> <http://www.orpha.net/ORDO/Orphanet_377795>)
- SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_179494> <http://www.orpha.net/ORDO/Orphanet_377788>)
- SubClassOf(<http://www.orpha.net/ORDO/Orphanet_179494> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_179490>))

@Deleted Classes

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_70470
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_70470> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70470> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_181425>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_70470> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70470> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409931>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_70470> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_338
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_338> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "7.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_338> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_338> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_338> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79386>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_338> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_338> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183487>))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_251636
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251636> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251636> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_251633>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_251636> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_251636> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409976>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C032> "0.16"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_251636> <http://www.orpha.net/ORDO/Orphanet_377797>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251636> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409941>))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_181425
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_181425> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_181425> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_181425> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_181425> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_181425> <http://www.orpha.net/ORDO/Orphanet_181422>)

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_75501
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_75501> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_275736>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_75501> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_75501> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_75501> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_230845
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_230845> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "3.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_233655>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_230845> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_230845> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_230845> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_82004
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_82004> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82004> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_285014>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82004> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82004> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_82004> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_82004> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409934>))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_99876
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99876> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_1899>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99876> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_99876> <http://www.orpha.net/ORDO/Orphanet_377795>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99876> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99876> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_99875
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99875> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_1899>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99875> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99875> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_99875> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_99875> <http://www.orpha.net/ORDO/Orphanet_377795>)

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_251643
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_251633>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409941>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_251643> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_251643> <http://www.orpha.net/ORDO/Orphanet_377797>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251643> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_251643> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>)))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_251639
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Histopathological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_251639> <http://www.orpha.net/ORDO/Orphanet_377797>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251639> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_251639> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_251633>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_251639> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C020> <http://www.orpha.net/ORDO/Orphanet_409979>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>)))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_90309
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90309> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_287>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90309> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90309> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_90309> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409984>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C028> "5.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_90309> <http://www.orpha.net/ORDO/Orphanet_377795>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90309> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_90318
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90318> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_90318> <http://www.orpha.net/ORDO/Orphanet_377795>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90318> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_287>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90318> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_90318> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))

---
!Deleted class!: IRI http://www.orpha.net/ORDO/Orphanet_317857
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_317857> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_70470>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_317857> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_317857> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19p13.3"^^xsd:string))

@New Classes

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_471328
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_471328> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "21q22.3"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_471328> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_471328> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_2065>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98068
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98068> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528105
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528105> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528105> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409947>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528105> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528105> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93603>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_528105> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528105> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183592>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_528105> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "22.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528105> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_528105> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538574
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_538574> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538574> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_140456>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538574> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98352>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_531247
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531247> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531247> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "1q42.13"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_531247> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_93213>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_531220
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531220> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_531220> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_93334>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531220> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "8q22.1"^^xsd:string))

---
!New class!: IRI https://creativecommons.org/licenses/by/4.0/

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535057
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535057> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "2q36.1"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535057> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535057> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_178506>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98122
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98122> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529799
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529799> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_529799> <http://www.orpha.net/ORDO/Orphanet_377792>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529799> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410224>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409976>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "0.87"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529799> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_415286>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_172979
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_172979> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156183
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156183> <http://www.orpha.net/ORDO/Orphanet_156165>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_156183> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156180
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156180> <http://www.orpha.net/ORDO/Orphanet_156165>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_156180> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156177
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156177> <http://www.orpha.net/ORDO/Orphanet_156165>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_156177> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156174
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_156174> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156174> <http://www.orpha.net/ORDO/Orphanet_156165>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156171
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156171> <http://www.orpha.net/ORDO/Orphanet_156165>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_156171> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156168
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_156168> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156168> <http://www.orpha.net/ORDO/Orphanet_156165>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156165
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156165> <http://www.orpha.net/ORDO/Orphanet_363250>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_156165> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156162
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156162> <http://www.orpha.net/ORDO/Orphanet_363250>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_156162> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_536545
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_536545> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536545> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_536532
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536532> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_536532> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536532> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93446>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538756
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538756> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_79386>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538756> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183487>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_538756> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529665
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529665> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529665> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529665> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529665> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "10.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529665> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529665> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_269523>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_529665> <http://www.orpha.net/ORDO/Orphanet_377789>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529665> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102283>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529665> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529665> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_269567>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98297
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98297> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528361
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528361> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528361> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "9p22.2-p22.1"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_528361> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_521445>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528371
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_528371> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_521406>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528371> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528371> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "8p21.3"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_536471
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_536471> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536471> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_536467
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_536467> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536467> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_309450>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536467> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_371195>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536467> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_536471>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536467> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536467> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93446>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536467> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_156071
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_156071> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_457252
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_457252> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530849
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530849> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_530849> <http://www.orpha.net/ORDO/Orphanet_377795>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530849> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_444490>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530838
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530838> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98349>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530838> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_530838> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_536391
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_536391> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536391> <http://www.orpha.net/ORDO/Orphanet_98053>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_250811
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_250811> <http://www.orpha.net/ORDO/Orphanet_250805>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_250811> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_250808
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_250808> <http://www.orpha.net/ORDO/Orphanet_250805>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_250808> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_67037
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_67037> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_519384
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_519384> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_519272>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Morphological anomaly"@en) <http://www.orpha.net/ORDO/Orphanet_519384> <http://www.orpha.net/ORDO/Orphanet_377791>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_172973
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_172973> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_172985
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_172985> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470906
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470906> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "9q34.12"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470906> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470906> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_478664>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470902
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470902> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "2p23.2"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470902> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_2701>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470902> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529328
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529328> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "20p11.21"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_529328> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_527450>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529328> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528623
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528623> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_250811>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528623> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91378>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_528623> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538096
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538096> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91024>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_538096> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528328
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_528328> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_521432>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528328> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528328> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "7q21.2"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470052
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470052> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470052> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19p13.3"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470052> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_238505>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_527468
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527468> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_180779>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527468> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527468> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_471383>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_527468> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527468> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_108973>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_527468> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "2.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_527468> <http://www.orpha.net/ORDO/Orphanet_377789>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527468> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_108979>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527468> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_108969>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527468> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_459787>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_527450
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527450> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527450> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_93441>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_527450> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_527450> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "5.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527450> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527450> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_139030>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_527450> <http://www.orpha.net/ORDO/Orphanet_377789>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529292
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529292> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529292> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "1q41"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_529292> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_527468>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529273
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_529273> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_528084>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529273> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "3q26.33"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529273> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98752
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98752> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98751
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98751> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98748
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98748> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98748> <http://www.orpha.net/ORDO/Orphanet_98743>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98744
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98744> <http://www.orpha.net/ORDO/Orphanet_98743>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98744> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98743
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98743> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98743> <http://www.orpha.net/ORDO/Orphanet_71859>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98740
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98740> <http://www.orpha.net/ORDO/Orphanet_98737>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98740> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98739
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98739> <http://www.orpha.net/ORDO/Orphanet_98737>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98739> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98738
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98738> <http://www.orpha.net/ORDO/Orphanet_98737>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98738> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98737
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98737> <http://www.orpha.net/ORDO/Orphanet_183497>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98737> <http://www.orpha.net/ORDO/Orphanet_71864>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98737> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98736
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98736> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530647
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_530647> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_93213>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530647> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "12q23.2"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530647> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470722
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470722> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_327767> <http://www.orpha.net/ORDO/Orphanet_178469>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470722> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470722> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "2p25.3"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535693
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535693> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535693> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "16q22.2"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535693> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_529970>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98695
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98695> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98742
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98742> <http://www.orpha.net/ORDO/Orphanet_98737>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98742> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98745
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98745> <http://www.orpha.net/ORDO/Orphanet_98743>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98745> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98746
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98746> <http://www.orpha.net/ORDO/Orphanet_98743>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98746> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98747
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98747> <http://www.orpha.net/ORDO/Orphanet_98743>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98747> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98749
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98749> <http://www.orpha.net/ORDO/Orphanet_98743>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98749> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98689
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98689> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98750
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98750> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98750> <http://www.orpha.net/ORDO/Orphanet_71864>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98753
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98753> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98667
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98667> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98069
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98069> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98558
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98558> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98532
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98532> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98531
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98531> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98530
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98530> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98528
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98528> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_363250
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_363250> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_363250> <http://www.orpha.net/ORDO/Orphanet_98053>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470582
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470582> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470582> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "20q13.33"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470582> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_521450>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530313
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530313> <http://www.orpha.net/ORDO/Orphanet_93460>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_530313> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530792
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530792> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_301>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_530792> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538863
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_538863> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538863> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_48104>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98470
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98470> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98469
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98469> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98468
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98468> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530298
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530298> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_530298> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530298> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_85110>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_531491
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531491> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531491> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "2q32.1"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_531491> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_276234>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535695
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535695> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "20q11.21"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535695> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535695> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_529970>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98103
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98103> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535893
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535893> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "19q13.2"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535893> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535893> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_465410> <http://www.orpha.net/ORDO/Orphanet_529831>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98124
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98124> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98301
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98301> <http://www.orpha.net/ORDO/Orphanet_98053>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98301> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_507998
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_507998> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_507998> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "10q26.3"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_507998> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_527497>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535702
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535702> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_528084>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535702> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q24.2"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535702> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535702> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317349> <http://www.orpha.net/ORDO/Orphanet_529962>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98298
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98298> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98296
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98296> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_366774
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_366774> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_366774> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_521414>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_366774> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "1p13.1"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_471160
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_471160> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_471160> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317349> <http://www.orpha.net/ORDO/Orphanet_521258>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_471160> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "Xq25"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_471178
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_471178> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_522077>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_471178> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_471178> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "12q21.2"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535685
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535685> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535685> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "8q24.3"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535685> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_529665>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_521268
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_521268> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98125
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98125> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98123
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98123> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98121
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98121> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98120
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98120> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98119
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98119> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98118
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98118> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98116
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98116> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98115
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98115> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98114
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98114> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98113
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98113> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98112
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98112> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98111
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98111> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98109
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98109> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98108
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98108> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98107
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98107> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98106
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98106> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98105
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98105> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98104
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98104> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98102
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98102> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98101
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98101> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470550
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470550> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "2p25.1"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470550> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_521390>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470550> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470184
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470184> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470184> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "16q22.2"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470184> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_791>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_502538
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_502538> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_791>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_502538> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_475>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_502538> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_502538> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "10q24.32"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_503304
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_503304> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_528105>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_503304> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "13q32.1"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_503304> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470162
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470162> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470162> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_465410> <http://www.orpha.net/ORDO/Orphanet_529828>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470162> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "10q23.33"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530995
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530995> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_86851>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_530995> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_527497
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527497> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_527497> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527497> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_527497> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_527497> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "25.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527497> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_68356>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527497> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527497> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_316240>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527497> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_527497> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530652
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_530652> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_417>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530652> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528663
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528663> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91385>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_528663> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98073
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98073> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98071
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98071> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98070
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98070> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98529
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98529> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538238
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538238> <http://www.orpha.net/ORDO/Orphanet_98743>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_538238> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530642
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_530642> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_93213>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530642> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530642> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q25"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535458
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535458> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_535458> <http://www.orpha.net/ORDO/Orphanet_377795>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535458> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_444490>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535453
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535453> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_444490>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535453> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_535453> <http://www.orpha.net/ORDO/Orphanet_377795>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_1092
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_1092> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98110
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98110> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98117
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98117> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530033
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530033> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530033> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_269550>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530033> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_269194>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Morphological anomaly"@en) <http://www.orpha.net/ORDO/Orphanet_530033> <http://www.orpha.net/ORDO/Orphanet_377791>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535393
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535393> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535393> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_3451>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535393> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "6p24.1"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535384
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535384> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "11q13.2"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535384> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535384> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_254688>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535378
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535378> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_254688>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535378> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "22q13.2"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535378> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535359
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535359> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535359> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "11p15.5"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535359> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_244>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535349
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535349> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q25.3"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535349> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535349> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_379>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535343
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535343> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535343> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "10q24.2"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535343> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_98994>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_509056
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_509056> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317345> <http://www.orpha.net/ORDO/Orphanet_900>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_509056> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "6p21.32"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_509056> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529852
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_529852> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529852> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529852> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_56044>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529852> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529852> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_424936>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529852> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_2703
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2703> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_269523>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2703> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "5.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_2703> <http://www.orpha.net/ORDO/Orphanet_377789>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2703> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102285>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2703> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_269567>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2703> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_458830>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2703> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_330206>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_2703> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_2703> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98643
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98643> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98664
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98664> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529828
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529828> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_306640>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Particular clinical situation in a disease or syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_529828> <http://www.orpha.net/ORDO/Orphanet_377793>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528340
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528340> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528340> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "Xp11.23"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_528340> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_2570>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530983
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530983> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530983> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530983> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_530983> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_530983> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "25.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_530983> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530983> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_537072
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_537072> <http://www.orpha.net/ORDO/Orphanet_377795>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_537072> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_528647>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_140503
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140503> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_300766
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300766> <http://www.orpha.net/ORDO/Orphanet_98301>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_300766> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_300766> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_300763
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300763> <http://www.orpha.net/ORDO/Orphanet_98301>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_300763> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_300763> <http://www.orpha.net/ORDO/Orphanet_377794>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_300758
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300758> <http://www.orpha.net/ORDO/Orphanet_98301>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_300758> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_300758> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_300755
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet validated"@en) <http://www.orpha.net/ORDO/Orphanet_300755> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_300755> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_300755> <http://www.orpha.net/ORDO/Orphanet_98301>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470736
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470736> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_2609>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470736> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "22q13.2"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470736> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_250805
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_250805> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_250805> <http://www.orpha.net/ORDO/Orphanet_98053>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470770
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470770> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "16q22.1"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470770> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470770> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_327767> <http://www.orpha.net/ORDO/Orphanet_529980>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538963
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538963> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_238510>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_538963> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538963> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_480549>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538958
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538958> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_238510>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_538958> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470150
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470150> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_178469>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470150> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "7q22.1"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470150> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538934
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538934> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_2442>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_538934> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538931
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_538931> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538931> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_2442>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_508976
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_508976> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_529965>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_508976> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "5q15-q21.1"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_508976> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_493542
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_493542> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_231183>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_493542> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_493542> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q24.2"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528295
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_528295> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_521438>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528295> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528295> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "2p21"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_531151
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_531151> <http://www.orpha.net/ORDO/Orphanet_377789>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_531151> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "10.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_531151> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531151> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531151> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531151> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531151> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531151> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_262074>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_140428
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140428> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_140432
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_140432> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_94091
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_94091> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_94091> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98506>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_98741
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_98741> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_98741> <http://www.orpha.net/ORDO/Orphanet_98737>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538872
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_538872> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538872> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_48104>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538869
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_538869> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538869> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_48104>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538866
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_538866> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538866> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_48104>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_519418
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_519418> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_521426>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_519418> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_519418> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "9p21.2"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535053
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535053> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_363999>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535053> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535053> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "13q14.3"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538634
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_538634> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_302>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538634> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "8q21.13"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538634> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529808
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_529808> <http://www.orpha.net/ORDO/Orphanet_377792>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529808> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410225>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "1.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529808> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410051>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "1.4"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529808> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_410031>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C026> <http://www.orpha.net/ORDO/Orphanet_409977>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C029> "1.49"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529808> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529808> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529808> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_415286>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528135
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528135> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "11q24"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528135> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Not yet assessed"@en) <http://www.orpha.net/ORDO/Orphanet_528135> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_90636>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_535830
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535830> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_528084>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_535830> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317349> <http://www.orpha.net/ORDO/Orphanet_529962>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535830> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "17q24.2"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_535830> <http://www.orpha.net/ORDO/Orphanet_410298>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529831
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529831> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_306640>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Particular clinical situation in a disease or syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_529831> <http://www.orpha.net/ORDO/Orphanet_377793>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_519357
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_519357> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_531241
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531241> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531241> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "11p11.2"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_531241> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_93213>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529962
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529962> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_262137>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529962> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102283>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529962> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_529962> <http://www.orpha.net/ORDO/Orphanet_377789>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529962> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529962> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409943>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529962> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529962> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "19.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529962> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_509234
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_509234> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_509234> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "6p25.2"^^xsd:string))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_509234> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_529977>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_172982
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_172982> <http://www.orpha.net/ORDO/ObsoleteClass>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529980
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529980> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529980> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529980> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_529974>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529980> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_529980> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529965
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529965> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102283>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529965> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "5.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529965> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183763>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529965> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409929>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Malformation syndrome"@en) <http://www.orpha.net/ORDO/Orphanet_529965> <http://www.orpha.net/ORDO/Orphanet_377789>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529965> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529965> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_102369>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529965> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529970
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529970> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529970> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529970> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529970> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_399808>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_529970> <http://www.orpha.net/ORDO/Orphanet_377796>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528647
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_528647> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528647> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91378>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529974
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529974> <http://www.orpha.net/ORDO/Orphanet_165655>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Group of phenomes"@en) <http://www.orpha.net/ORDO/Orphanet_529974> <http://www.orpha.net/ORDO/Orphanet_377794>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529974> <http://www.orpha.net/ORDO/Orphanet_104012>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529974> <http://www.orpha.net/ORDO/Orphanet_169361>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529977
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529977> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_271870>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529977> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529977> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529977> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C016> <http://www.orpha.net/ORDO/Orphanet_409930>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529977> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529977> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "7.0"^^xsd:float)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529977> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_529974>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_529977> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529977> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_182231>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_530303
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530303> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409949>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530303> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409948>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Clinical subtype"@en) <http://www.orpha.net/ORDO/Orphanet_530303> <http://www.orpha.net/ORDO/Orphanet_377796>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_530303> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_85110>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_536516
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_536516> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536516> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_97242>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_536516> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_98249>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_537891
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_537891> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_528647>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Etiological subtype"@en) <http://www.orpha.net/ORDO/Orphanet_537891> <http://www.orpha.net/ORDO/Orphanet_377795>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538101
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_538101> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538101> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_91024>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_529468
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529468> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_68347>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_529468> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409950>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_529468> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_529468> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528084
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528084> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_183757>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528084> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_87277>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528084> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409946>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_528084> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409981>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528084> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409945>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_528084> <http://www.orpha.net/ORDO/Orphanet_377788>)

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_531206
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531206> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_531206> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_98892>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_531206> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "1q42.13"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_528091
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528091> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C017> <http://www.orpha.net/ORDO/Orphanet_409944>))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000218> "Disease"@en) <http://www.orpha.net/ORDO/Orphanet_528091> <http://www.orpha.net/ORDO/Orphanet_377788>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_528091> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C024> "1.0"^^xsd:float)))
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Validated"@en) <http://www.orpha.net/ORDO/Orphanet_528091> ObjectIntersectionOf(ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C022> <http://www.orpha.net/ORDO/Orphanet_409991>) ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_C025> <http://www.orpha.net/ORDO/Orphanet_409979>)))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_528091> ObjectSomeValuesFrom(<http://purl.obolibrary.org/obo/BFO_0000050> <http://www.orpha.net/ORDO/Orphanet_35696>))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_538628
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538628> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_538628> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_410295> <http://www.orpha.net/ORDO/Orphanet_124>))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_538628> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "16p12.3"^^xsd:string))

---
!New class!: IRI http://www.orpha.net/ORDO/Orphanet_470098
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470098> DataHasValue(<http://www.orpha.net/ORDO/Orphanet_C040> "15q26.1"^^xsd:string))
+ SubClassOf(<http://www.orpha.net/ORDO/Orphanet_470098> <http://www.orpha.net/ORDO/Orphanet_410298>)
+ SubClassOf(Annotation(<http://purl.obolibrary.org/obo/ECO_0000205> "Assessed"@en) <http://www.orpha.net/ORDO/Orphanet_470098> ObjectSomeValuesFrom(<http://www.orpha.net/ORDO/Orphanet_317343> <http://www.orpha.net/ORDO/Orphanet_302>))